NAD+ 500mg

Vials

NAD+ 500mg

Nicotinamide adenine dinucleotide, a coenzyme central to cellular energy production and DNA repair research.

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every living cell, central to metabolism, energy production, and DNA repair. It serves as an essential cofactor for hundreds of enzymatic reactions, including those governing mitochondrial energy output and sirtuin-mediated longevity pathways. Cellular NAD+ levels are well documented to decline with age, a decline linked in research to reduced mitochondrial efficiency and impaired DNA repair capacity — making NAD+ replenishment a frequent subject of longevity and cellular-energy research. Research and wellness-clinic protocols commonly use 50-100mg per subcutaneous injection, 2-3 times weekly, or 100-500mg per intravenous session for faster delivery. Direct pharmacokinetic data on injectable NAD+ (peak levels, elimination half-life) remains a notably understudied area of the literature, so dosing intervals in practice are guided more by protocol convention than by published half-life figures. Each vial is supplied at 500mg.

Independent laboratory documentation

Certificates of Analysis

View the laboratory reports currently published for this product.

Certificate of Analysis

Specifications

Peptide
NAD+
Dosage
500mg/vial
Form
Lyophilised

Research Benefits

  • Cellular energy production — Serves as an essential cofactor in mitochondrial ATP generation.
  • DNA repair support — Required by PARP enzymes involved in repairing damaged DNA.
  • Sirtuin pathway research — Investigated as a substrate for sirtuins, enzymes linked to cellular longevity regulation.
  • Cellular communication — Studied for its role as a signalling substrate across multiple metabolic pathways.
  • Established dosing conventions — Common research protocols run 50-100mg subcutaneously 2-3x weekly, or 100-500mg per IV session.

How It Works

NAD+ functions as a coenzyme, shuttling electrons in the redox reactions that generate cellular energy within the mitochondria. It is also a required substrate for PARP enzymes, which repair damaged DNA, and for sirtuins, a family of enzymes studied extensively for their role in cellular ageing and longevity regulation.

Because NAD+ levels decline measurably with age, and this decline is linked to reduced mitochondrial efficiency and DNA-repair capacity, direct NAD+ administration is studied as a way of replenishing the coenzyme pool more directly than upstream precursors like NMN or NR. Its own pharmacokinetics as an injectable — how quickly it's cleared once administered — are less well characterised in the literature than its downstream biological roles.

⚠ For Research Use Only

This product is supplied strictly for in-vitro laboratory and preclinical research use. It is not a drug, food, dietary supplement, or cosmetic, and is not intended for human or animal consumption, diagnosis, treatment, or prevention of any disease. NAD+ 500mg must be handled only by qualified individuals trained in proper laboratory safety procedures.

By purchasing, the buyer confirms this product is being acquired for legitimate research purposes and assumes full responsibility for its handling, storage, and use in compliance with all applicable local, national, and international laws.

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