IGF-1 LR3 1mg

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IGF-1 LR3 1mg

A long-acting IGF-1 analogue with a 20-30 hour half-life, verified at 98% purity and 1.07mg content.

IGF-1 LR3 is a synthetic 83-amino-acid analogue of Insulin-like Growth Factor 1, modified with a 13-amino-acid N-terminal extension and a single amino-acid substitution that dramatically reduces its binding to IGF-binding proteins. Where native IGF-1 clears from circulation within minutes, LR3 remains bioactive for roughly 20-30 hours. Independent lab testing confirmed the finished vial at 98% purity with an actual content of 1.07mg against the 1mg label claim. Reconstitute with bacteriostatic water.

Specifications

Peptide
IGF-1 LR3
Also Known As
Long R3 IGF-1
Dosage
1mg/vial
Purity
98%
Verified Content
1.07mg
Form
Lyophilised
Half-Life
20-30 hours
Storage
2-8°C

Research Benefits

  • Muscle hyperplasia research — Studied for stimulating the formation of new muscle cells rather than simply enlarging existing ones.
  • Extended bioactivity — The LR3 modification extends active half-life from minutes to over 20 hours compared to native IGF-1.
  • Cellular proliferation — Investigated for satellite cell activation, differentiation, and muscle fibre recruitment.
  • Nutrient partitioning — Studied for directing nutrients preferentially toward muscle tissue over fat storage.
  • Verified potency — Independently confirmed at 98% purity and 1.07mg content.

How It Works

IGF-1 LR3 combines a 13-amino-acid N-terminal extension with a single arginine-for-glutamic-acid substitution at position 3, a structural change that sharply reduces the molecule's affinity for IGF-binding proteins (IGFBPs). Because native IGF-1 is normally sequestered and cleared by IGFBPs within minutes, this modification is what allows LR3 to remain bioactive in circulation for roughly a full day.

Once active, it binds the IGF-1 receptor with an affinity similar to native IGF-1, driving anabolic signalling through the PI3K/Akt/mTOR pathway, alongside research interest in nutrient partitioning, insulin sensitivity, and satellite cell recruitment relevant to skeletal muscle growth research.

⚠ For Research Use Only

This product is supplied strictly for in-vitro laboratory and preclinical research use. It is not a drug, food, dietary supplement, or cosmetic, and is not intended for human or animal consumption, diagnosis, treatment, or prevention of any disease. IGF-1 LR3 1mg must be handled only by qualified individuals trained in proper laboratory safety procedures.

By purchasing, the buyer confirms this product is being acquired for legitimate research purposes and assumes full responsibility for its handling, storage, and use in compliance with all applicable local, national, and international laws.

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