Vials

Epitalon 10mg

Name: Epitalon 10mg
Brand: Quanta Pharmaceuticals

A pineal tetrapeptide studied for telomerase activation, circadian regulation and cellular longevity research.

Epitalon (Epithalon, Epithalone) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modelled on Epithalamin, a polypeptide naturally produced by the pineal gland. Originally developed by Professor Vladimir Khavinson's laboratory at the St. Petersburg Institute of Bioregulation and Gerontology, it has become one of the most discussed compounds in longevity science. In cultured human fibroblast lines, Epitalon has been shown to activate hTERT expression, increase telomerase activity, and extend proliferative lifespan well beyond the Hayflick limit — a 2025 independent replication at Brunel University London reproduced this in-vitro effect. Importantly, no completed human clinical trial has yet measured telomere length in living subjects before and after Epitalon administration, so whether the in-vitro effect translates to a living human body remains an open question rather than an established fact. Each vial is supplied at 10mg of lyophilised peptide.

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Specifications

Peptide

Epitalon

Sequence

Ala-Glu-Asp-Gly

Dosage

10mg/vial

Form

Lyophilised

Administration

Subcutaneous

Research Benefits

Telomerase activation (in vitro) — Independently replicated research shows Epitalon activates hTERT and telomerase activity in cultured human cell lines.
Extended replicative lifespan (in vitro) — Treated human fibroblast lines have divided well beyond the Hayflick limit in laboratory studies.
Pineal gland support — Originally developed to help restore pineal gland function and melatonin production.
Sleep quality — Research suggests improvements in circadian rhythm regulation and sleep architecture.
Neuroendocrine function — Investigated for normalising anterior pituitary hormones and overall endocrine balance.

How It Works

Epitalon's primary studied mechanism is activation of telomerase, the enzyme that adds protective repeats to the ends of chromosomes. Telomeres shorten with each cell division, eventually contributing to cellular senescence; in cultured human fibroblast lines, Epitalon treatment has been shown to activate hTERT expression and extend proliferative lifespan beyond the Hayflick limit, a finding independently replicated at Brunel University London in 2025.

Separately, Epitalon has been studied for restoring pineal gland function, including melatonin production in ageing research subjects, with implications for sleep quality, circadian rhythm, and broader neuroendocrine regulation. It's worth noting for research planning that the telomerase findings so far are cell-culture results — no controlled human trial has yet measured telomere length change in living subjects, so the in-vitro-to-in-vivo translation remains unproven.

⚠ For Research Use Only

This product is supplied strictly for in-vitro laboratory and preclinical research use. It is not a drug, food, dietary supplement, or cosmetic, and is not intended for human or animal consumption, diagnosis, treatment, or prevention of any disease. Epitalon 10mg must be handled only by qualified individuals trained in proper laboratory safety procedures.

By purchasing, the buyer confirms this product is being acquired for legitimate research purposes and assumes full responsibility for its handling, storage, and use in compliance with all applicable local, national, and international laws.