KPV 10mg

Vials

KPV 10mg

An alpha-MSH-derived tripeptide studied for anti-inflammatory action in gut, skin and immune research.

KPV (Lys-Pro-Val) is the C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH). It retains α-MSH's anti-inflammatory activity while leaving out the parent hormone's pigmentation and other effects, making it a targeted tool for inflammation research. Each vial is supplied at 10mg of lyophilised peptide.

Specifications

Peptide
KPV
Sequence
Lys-Pro-Val
Dosage
10mg/vial
Form
Lyophilised
Administration
Subcutaneous

Research Benefits

  • Anti-inflammatory action — Research shows KPV inhibits inflammatory pathways including NF-κB and pro-inflammatory cytokines.
  • Gut health research — Studied extensively in models of inflammatory bowel disease, colitis, and intestinal inflammation.
  • Immune modulation — Demonstrates the ability to regulate immune responses without broad immunosuppression.
  • Skin health interest — Investigated for wound healing and inflammatory skin conditions.
  • Antimicrobial properties — Some research indicates activity against certain bacteria and fungi.

How It Works

KPV works primarily by inhibiting NF-κB activation, a key transcription factor that drives the production of pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α. Because it is derived only from the C-terminal fragment of α-MSH, it retains this anti-inflammatory signalling without affecting melanin production or the parent hormone's other systemic effects.

Research has also shown KPV can enter cells — and even the nucleus — where it interacts directly with inflammatory signalling cascades, an intracellular action considered central to its potent anti-inflammatory profile in research models.

⚠ For Research Use Only

This product is supplied strictly for in-vitro laboratory and preclinical research use. It is not a drug, food, dietary supplement, or cosmetic, and is not intended for human or animal consumption, diagnosis, treatment, or prevention of any disease. KPV 10mg must be handled only by qualified individuals trained in proper laboratory safety procedures.

By purchasing, the buyer confirms this product is being acquired for legitimate research purposes and assumes full responsibility for its handling, storage, and use in compliance with all applicable local, national, and international laws.

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