Orals

Cardarine 10mg

Name: Cardarine 10mg
Brand: Quanta Pharmaceuticals

GW501516, a PPARδ agonist studied for endurance, fat metabolism and cardiovascular performance research.

Cardarine (GW501516) is a PPARδ (peroxisome proliferator-activated receptor delta) agonist widely studied in endurance and metabolic research. This formulation supplies 60 tablets of 10mg per tub. Chemically classified as C21H18F3NO3S2, Cardarine activates PPARδ, a nuclear receptor that regulates genes governing fatty acid transport and oxidation in skeletal muscle. Research has focused on its capacity to shift substrate utilisation toward fat, alongside reported improvements in exercise capacity and lipid markers in preclinical models. Original clinical development, by GlaxoSmithKline, was discontinued in 2007 after long-term rodent studies at high doses (3mg/kg/day) showed accelerated tumour development in multiple organs; the World Anti-Doping Agency added it to its prohibited list in 2009. It remains widely used as a preclinical and in-vitro research tool, but human safety data at any dose is limited, and researchers should weigh this history carefully.

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Specifications

Tablets

Dose Per Tablet

10mg

Half-Life

16-24 hours

Administration

Oral

Chemical Structure

C21H18F3NO3S2

Research Benefits

Enhanced Endurance — PPARδ activation is studied for improving exercise capacity and stamina in preclinical models.
Fat Metabolism — Research reports a shift toward fat as a preferred fuel source during activity.
Cardiovascular Markers — Investigated for favourable changes in lipid profile in research settings.
Mitochondrial Gene Expression — Studied for upregulating genes involved in mitochondrial fatty-acid oxidation.
Stable Once-Daily Dosing — A 16-24 hour half-life supports consistent receptor engagement from a single daily dose.

How It Works

GW501516 is a potent and selective agonist of PPARδ, a nuclear receptor highly expressed in skeletal muscle that governs the transcription of genes involved in fatty acid transport and oxidation.

By activating PPARδ, Cardarine shifts cellular metabolism toward greater reliance on fat as a fuel source, a mechanism studied for its downstream effects on endurance capacity and lipid handling. Its 16-24 hour half-life allows for consistent once-daily dosing in research protocols. Note that its original drug-development programme was halted over carcinogenicity signals seen in animal studies at high doses — a key part of its research history that any protocol design should account for.

⚠ For Research Use Only

This product is supplied strictly for in-vitro laboratory and preclinical research use. It is not a drug, food, dietary supplement, or cosmetic, and is not intended for human or animal consumption, diagnosis, treatment, or prevention of any disease. Cardarine 10mg must be handled only by qualified individuals trained in proper laboratory safety procedures.

By purchasing, the buyer confirms this product is being acquired for legitimate research purposes and assumes full responsibility for its handling, storage, and use in compliance with all applicable local, national, and international laws.